Pack Size : 96 Well

Package Kit Components :

• Microwells  coated
• Ferritin Standards
• Anti-Ferritin Biotin Reagent
• Anti-Ferritin Enzyme Reagent
• TMB Reagent
• Stop Solution
• Wash concentrate
• Technical Insert

Usage : The New life  Ferritin ELISA Kit is intended for the quantitative measurement of Ferritin in human serum or plasma.

Description : Human Ferritin is a large molecule with a molecular weight of approximately 450,000 Daltons, and consists of a protein shell around an iron core; each molecule of Ferritin may contain as many as 4,000 iron atoms.  Under normal conditions, this may represent 25% of the total iron found in the body.  In addition, Ferritin can be found in several isomers. High concentrations of Ferritin are found in the cytoplasm of the reticuloendothelial system, the liver, spleen and bone marrow.  Methods previously used to measure iron in such tissues are invasive, cause patient trauma and lack adequate sensitivity. The measurement of Ferritin in serum is useful in determining changes in body iron storage, and is non-invasive with relatively little patient discomfort.  Serum Ferritin levels can be measured routinely and are particularly useful in the early detection of iron-deficiency anemia in apparently healthy people. Serum Ferritin measurements are also clinically significant in the monitoring of the iron status of pregnant women, blood donors, and renal dialysis patients.  High Ferritin levels may indicate iron overload without apparent liver damage, as may be noted in the early stages of idiopathic hemochromatosis.  Ferritin levels in serum have also been used to evaluate clinical conditions not related to iron storage, including inflammation, chronic liver disease, and malignancy.